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Version 4.0.200811 |
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This is the complete description of the cell line that you requested.
By selecting a generic term (e.g. SPECIES) you will go to the corresponding list of controlled terms, while by selecting a specific term you will go to the list of corresponding cell line names.
DSMZ catalog code: ACC 78
SPECIES: human, African
TUMOR: lymphoma, Burkitt
Endogenous viruses: contains Epstein-Barr
Available in the following LABORATORY:
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German Collection of Microorganisms and Cell Cultures (DSMZ, Braunschweig)
mycoplasma negative, DAPI, broth-agar, hybridization
Validated by: cytogenetics 1 (near diploid with 20% polyploidy; 46(45-48)<2n>XY/XXY, +7, -9, t(8;14)(q24;q32)) * DNA fingerprinting (unique Hinf I-(gtg)5 DNA profile) * immunological analysis (CD3- CD10+ CD13- CD19+ CD37+ HLA-DR+ smIgG- smIgM+ sm+ sm-) * isoenzymes (confirmed as human with IEF of AST, NP, PEP B) * reverse transcriptase (reverse transcriptase negative)
Availability in cell line catalogues: ATCC: CCL 213, ECACC: 85011437, ICLC: HTL95024, IZSBS: BS TCL 104
Bibliographic references:
- Cancer Res 1968;28:1300-1310 - PMID: 4174339
- Clin Exp Immunol 1976;25:367-368 - PMID: 963908
- Int J Cancer 1977;19:334-337
- Tissue Antigens 1978;11:96-112 - PMID: 77067
ECACC catalog code: 85011437
SPECIES: human, Black
TISSUE/ORGAN: blood
TUMOR: lymphoma, Burkitt
Endogenous viruses: contains Epstein-Barr
Available in the following LABORATORY:
Availability in cell line catalogues: ATCC: CCL 213, DSMZ: ACC 78, ICLC: HTL95024, IZSBS: BS TCL 104
Bibliographic references:
- Cancer Res 1968;28:1300-1310 - PMID: 4174339
- Clin Exp Immunol 1976;25:367-368 - PMID: 963908
- Int J Cancer 1977;19:334-337
- Tissue Antigens 1978;11:96-112 - PMID: 77067
ICLC catalog code: HTL95024
Continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human, Black (male, 16 years old)
TUMOR: lymphoma, Burkitt
tumorigenic in nude mice
Endogenous viruses: contains Epstein-Barr
DEPOSITOR: Obtained from ECACC.
Cell line available for distribution. For non-commercial investigative use only
PROPERTIES: complement receptor; Fc receptor; tumor markers; target line; differentiation; antitumour testing; tumorigenicity; virology
Available in the following LABORATORY:
-
Istituto Nazionale per la Ricerca sul Cancro c/o CBA (ICLC, Genova)
RPMI 1640 + 10% FBS + 2mM L-Glutamine; Freezing medium: Culture medium + 50% FBS + 10% DMSO; Maintain cultures between 2 and 9 x 105 cells/ml; 37C, 5% CO2 , mycoplasma negative, HOECHST and PCR
Handle under Biosafety Level 2 containment
Validated by: HLA-DP beta (confirmed as human by PCR) * isoenzymes (confirmed as human with MD, NP)
Availability in cell line catalogues: ECACC: 85011437, DSMZ: ACC 78, IZSBS: BS TCL 104
Bibliographic references:
- Cancer Res 1968;28:1300-1310 - PMID: 4174339
- Clin Exp Immunol 1976;25:367-368 - PMID: 963908
- Int J Cancer 1977;19:334-337
- J Exp Med 1976;143:1528-1533 - PMID: 1083890
- Tissue Antigens 1978;11:96-112 - PMID: 77067
IZSBS catalog code: BS TCL 104
Continuous culture, grown as suspension
Lymphoblast-like morphology
SPECIES: human, Black (male, 16 years old) Karyology: 2n = 46 in 50 cells
TUMOR: lymphoma, Burkitt
tumorigenic in nude mice
DEPOSITOR: obtained from ATCC
PROPERTIES: well characterized as B lymphoblast cell line employed in studies on leukemogenesis mechanisms
Available in the following LABORATORY:
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Istituto Zooprofilattico Sperimentale (IZSBS, Brescia)
RPMI 1640 + 10% FBS; Freezing medium: Culture medium + 10% DMSO; 37C, 5% CO2 , mycoplasma negative, culture
Validated by: isoenzymes (confirmed as human with NP, G6PD, MPI, PEPB, AST)
Availability in cell line catalogues: ATCC: CCL-213, ECACC: 85011437, DSMZ: ACC 78, ICLC: HTL95024
Bibliographic references:
- Cancer Res 1968;28:1300-1310 - PMID: 4174339
Continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human, Black (male, 16 years old)
TUMOR: lymphoma, Burkitt
tumorigenic in nude mice
Endogenous viruses: contains Epstein-Barr
PROPERTIES: complement receptor; Fc receptor; tumor markers; target line; differentiation; antitumour testing; tumorigenicity; virology
Available in the following LABORATORY:
Availability in cell line catalogues: ATCC: CCL 213, ECACC: 85011437, DSMZ: ACC 78, ICLC: HTL95024, IZSBS: BS TCL 104
Bibliographic references:
- Cancer Res 1968;28:1300-1310 - PMID: 4174339
- Clin Exp Immunol 1976;25:367-368 - PMID: 963908
- Int J Cancer 1977;19:334-337
- Tissue Antigens 1978;11:96-112 - PMID: 77067
Continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human, Black (male, 16 years old)
TUMOR: lymphoma, Burkitt
tumorigenic in nude mice
Endogenous viruses: contains Epstein-Barr
PROPERTIES: complement receptor; Fc receptor; tumor markers; target line; differentiation; antitumour testing; tumorigenicity; virology
Available in the following LABORATORY:
Availability in cell line catalogues: ATCC: CCL 213, ECACC: 85011437, DSMZ: ACC 78, ICLC: HTL95024, IZSBS: BS TCL 104
Bibliographic references:
- Cancer Res 1968;28:1300-1310 - PMID: 4174339
- Clin Exp Immunol 1976;25:367-368 - PMID: 963908
- Int J Cancer 1977;19:334-337
- Tissue Antigens 1978;11:96-112 - PMID: 77067
Continuous culture, grown as suspension
lymphoblast-like morphology
SPECIES: human, Black (male, 16 years old)
TUMOR: lymphoma, Burkitt
tumorigenic in nude mice
Endogenous viruses: contains Epstein-Barr
PROPERTIES: complement receptor; Fc receptor; tumor markers; target line; differentiation; antitumour testing; tumorigenicity; virology
Available in the following LABORATORY:
Availability in cell line catalogues: ATCC: CCL 213, ECACC: 85011437, DSMZ: ACC 78, ICLC: HTL95024, IZSBS: BS TCL 104
Bibliographic references:
- Cancer Res 1968;28:1300-1310 - PMID: 4174339
- Clin Exp Immunol 1976;25:367-368 - PMID: 963908
- Int J Cancer 1977;19:334-337
- Tissue Antigens 1978;11:96-112 - PMID: 77067
For information, get in touch with:
Istituto Nazionale per la Ricerca sul Cancro,
c/o Centro Biotecnologie Avanzate, Torre B - Piano 2
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Tel: +39-0105737-289, Fax: +39-0105737-295
Email: assunta.manniello@istge.it