Molecular Probe Data Base

The Molecular Probe Data Base (MPDB) contains information on synthetic oligonucleotides with a sequence of up to 100 nucleotides. Data are mainly taken from the literature and are encoded on the basis of controlled vocabularies.
At the moment MPDB is searchable through some SRS servers.
The SRS Servers through which it is possible to search MPDB (that is called MOLPROBE in this context) are the following:

• SRS 7.1.1 Server at the National Cancer Research Institute of Genoa, Italy
• SRS 5.1 Server at the Research Center of Computational and Biotechnological Sciences of the Second University of Naples

MPDB can easily be retrieved from our FTP server, together with SRS syntax files.
See FTP Site

Typology

• ca. 4300 oligonucleotides
• 821 different genes, of which 691 human and 112 viral
• ca. 3536 oligonucleotides are human gene specific
• ca. 620 oligonucleotides are viral gene specific

Applications

• 1944 genetic polymorphisms
• 834 human inherited disease diagnosis
• 517 cancer diagnosis
• 40 autoimmune disease diagnosis
• 72 neurologic disease diagnosis
• 517 infectious disease diagnosis

The most relevant data refer to:

• Identification (name, typology and nucleotide sequence)
• Target gene (name, HGM code, map location, EMBL accession number, allelic variants recognized)
• Applications
• Methods (PCR amplimers, RTPCR primers, DGGE analysis etc.)
• Retrieval sources (bibliographic references, distributors, catalogue codes,...)

For information, get in touch with: