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This is the complete description of the cell line that you requested.
By selecting a generic term (e.g. SPECIES) you will go to the corresponding list of controlled terms, while by selecting a specific term you will go to the list of corresponding cell line names.
SPECIES: human
TISSUE/ORGAN: lymph node
TUMOR: carcinoma, small cell
ECACC catalog code: 96020717
Morphology: Floating aggregates
Description: Human lung small cell carcinoma
Viruses: See Properties
Depositor: Dr P Twentyman, UKCCCR, Lincolns Inn Fields, London, UK (Originator)
No restrictions. Patent: None Specified By Depositor
Properties: Applications: Cytotoxicity studies, study of small cell lung cancer
Available in the following LABORATORY:
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Part of the Business Division of the Health Protection Agency (ECACC, Salisbury, Wiltshire)
RPMI 1640 + 2mM Glutamine + 10% Fetal Bovine Serum (FBS). Maintain cultures between 3-9x100,000 cells/ml; 5% CO2; 37C.
The cell line COR-L24 was established from a lymph node biopsy of an untreated 71 year-old male and was diagnosed as small cell lung carcinoma (SCLC). Bone marrow taken from the same patient contained hypercellular marrow consistent with normal haemopoietic cells and no evidence of neoplasm. In culture, this xenograft forming cell line grows as floating aggregates of packed cells with irregular shape. Cell line COR-L103 (96020735) was established from the same patient, having been isolated after treatment.
Research council deposit: Yes;
Price Code: C;
Validated by: isoenzymes (species confirmation)
Bibliographic references:
- Br J Cancer 1985;52:495 - PMID: 2998422
- Cancer Res 1992;52:5674 - PMID: 1327513
For information, get in touch with:
Istituto Nazionale per la Ricerca sul Cancro,
c/o Centro Biotecnologie Avanzate, Torre B - Piano 2
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Tel: +39-0105737-289, Fax: +39-0105737-293
Email: assunta.manniello@istge.it