CA46

Version 4.0.200811

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CA46 (human, ascitic fluid, lymphoma, Burkitt)

SPECIES: human
TISSUE/ORGAN: ascitic fluid
TUMOR: lymphoma, Burkitt

ECACC catalog code: 95010509
Morphology: Lymphoblast
Description: Human Burkitt's Lymphoma
Viruses: See Properties
Depositor: Obtained from ATCC, USA
No restrictions. Patent: None Specified By Depositor
Properties: Receptors: Surface Immunoglobulin M (IgM) (kappa) Products: Expresses surface Immunoglobulin M (IgM) (kappa)and secretes Immunoglobulin M (IgM) which does not bind to protein A.

Available in the following LABORATORY:

Part of the Business Division of the Health Protection Agency (ECACC, Salisbury, Wiltshire)
RPMI 1640 + 2mM Glutamine + 20% Fetal Bovine Serum (FBS). Maintain cultures at 5-9x100,000 cells/ml; 5% CO2; 37C.
Passages: +3; Derived from ascites fluid of a patient with Burkitt's Lymphoma. The cells are Epstein Barr Virus Nuclear Antigen (EBNA) negative. CA46 also expresses surface IgM kappa and secretes IgM which does not bind to protein A. Twelve percent of the cells expressed complement receptors whereas Fc receptors were undetectable.
Research council deposit: No; Price Code: C;
Validated by: isoenzymes (species confirmation)

Availability in cell line catalogues: ATCC: CRL 1648, ICLC: HTL97007

Bibliographic references:

J Immunol 1982;129:1336-1342 - PMID: 6286763
J Natl Cancer Inst 1980;64:477-483 - PMID: 6243722