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This is the complete description of the cell line that you requested.
By selecting a generic term (e.g. SPECIES) you will go to the corresponding list of controlled terms, while by selecting a specific term you will go to the list of corresponding cell line names.
SPECIES: human
TISSUE/ORGAN: blood
TUMOR: leukemia, T cell
ECACC catalog code: 88051601
Morphology: Lymphocyte
Description: Human T cell leukaemia
Viruses: See Properties
Depositor: Dr J Clarke, CAMR, Porton Down, Salisbury, UK
No restrictions. Patent: None Specified By Depositor
Properties: Products: Human T Lymphotrohpic Virus 1 (HTLV-1) tat gene Applications: Virus studies: support growth of HIV
Available in the following LABORATORY:
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Part of the Business Division of the Health Protection Agency (ECACC, Salisbury, Wiltshire)
RPMI 1640 + 2mM Glutamine + 10% Fetal Bovine Serum (FBS). Maintain cultures between 3-9x100,000 cells/ml; 5% CO2; 37C.
Clone of C63/CRII-4 derived by fusion of primary umbilical cord blood cells with HTLV-1 producing line from adult T cell leukaemia lymphoma patient. Contain defective HTLV-1 genome. In presence of HIV cells fuse to form syncytia. The cells should be handled under laboratory containment level 2.
Research council deposit: No;
Price Code: B;
Validated by: isoenzymes (species confirmation)
Bibliographic references:
- Nature 1983;303:253 - PMID: 6341859
- Science 1984;381 - PMID: 6330891
- Virology 1983;129:51 - PMID: 6412453
- Virology 1987;158:44 - PMID: 3107214
For information, get in touch with:
Istituto Nazionale per la Ricerca sul Cancro,
c/o Centro Biotecnologie Avanzate, Torre B - Piano 2
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Tel: +39-0105737-289, Fax: +39-0105737-293
Email: assunta.manniello@istge.it