Short cv
Presently Domenico Bordo is senior scientist at the National Cancer Research Institute (IST). He has been group leader of the Bioinformatics Group at the same Institute between 2002 and 2005. Previously he has been research investigator in the group of Structural Biology Laboratory of IST and of the University of Genova lead by Martino Bolognesi. He started his scientific career at IST. In 1988 he moved as post-doc (and later for one year as staff scientist) at EMBL-Heidelberg where he stayed until 1991. In 1991 he moved back to Genova as research assistant at IST, where he continued his scientific activities in the field of Bioinformatics applied to oncology. In 1995 he started working in the field of X-ray Crystallography with Martino Bolognesi, and he also spent a sabbatical year in the Laboratory of Biophysical Chemistry of the University of Groningen lead by Bauke Dijkstra. During his career he has also continued the collaboration with scientists of EMBL-Heidelberg, including Matti Saraste and Peer Bork. He is adopting a combined approach to study protein structure and function, which includes experimental, crystallographic and computational biology methods.
Since 2002 he is adjunt professor (professore a contratto) of Bioinformatics at the University of Genova. He holds the courses of Bioinformatics I and Bioinformatics II of the Biotechnology Curriculum and Bioinformatics I and II of the Physics curriculum.

Selected publications
Mukhopadhyay R., Bisacchi D., Zhou Y., Armirotti A., Bordo D. (2009).
Structural Characterization of the As/Sb Reductase LmACR2 from Leishmania major.
J Mol Biol. 386, 1229-1239.

Bocciardi R, Bordo D, Di Duca M, Di Rocco M, Ravazzolo R. (2009).
Mutational analysis of the ACVR1 gene in Italian patients affected with fibrodysplasia ossificans progressiva: confirmations and advancements.
Eur J Hum Genet. 17, 311-318.

Degiorgio D., Colombo C., Seia M., Porcaro L., Costantino L., Zazzeron L., Bordo D., Coviello D.A.. (2007).
Molecular characterization and structural implications of 25 new ABCB4 mutations in progressive familial intrahepatic cholestasis type 3 (PFIC3).
Eur J Hum Genet. 15, 1230-1228.

Bisacchi D., Zhou Y., Rosen B.P., Mukhopadhyay R., Bordo D. (2006).
Crystallization and preliminary crystallographic characterization of LmACR2, an arsenate/antimonate reductase from Leishmania major.
Acta Crystallogr Sect F 62, 976-979.

Gangemi R.M., Daga A., Muzio L., Marubbi D., Cocozza S., Perera M., Verardo S., Bordo D., Griffero F., Capra M.C., Mallamaci A., Corte G. (2006).
Effects of Emx2 inactivation on the gene expression profile of neural precursors.
Eur J Neurosci. 2006 Jan;23(2):325-334.

Spallarossa, A., Forlani, F., Carpen, A., Armirotti, A., Pagani, S., Bolognesi, M., Bordo, D. (2004).
The "Rhodanese" Fold and Catalytic Mechanism of 3-Mercaptopyruvate Sulfurtransferases: Crystal Structure of SseA from Escherichia coli.
J. Mol. Biol. 235, 583-593.

Ponassi, M., Cantoni, C., Biassoni, R., Conte, R., Spallarossa, A., Moretta, A., Moretta. L., Bolognesi, M., Bordo, D. (2003).
Expression and crystallographic characterization of the extracellular domain of human Natural Killer cell triggering receptor NKp46.
Acta Cryst. D59, 2259-2261.

Spallarossa A, Forlani F, Pagani S, Salvati L, Visca P, Ascenzi P, Bolognesi M, Bordo D. (2003).
Inhibition of Azotobacter vinelandii rhodanese by NO-donors.
Biochem Biophys Res Commun. 306, 1002-1007.

Cantoni C, Ponassi M, Biassoni R, Conte R, Spallarossa A, Moretta A, Moretta L, Bolognesi M, Bordo D. (2003).
The three-dimensional structure of the human NK cell receptor NKp44, a triggering partner in natural cytotoxicity.
Structure, 11, 725-34.

Spallarossa A, Carpen A, Forlani F, Pagani S, Bolognesi M, Bordo D. (2003).
SseA, a 3-mercaptopyruvate sulfurtransferase from Escherichia coli: crystallization
and preliminary crystallographic data.
Acta Crystallogr D59, 168-170.

Cantoni C., Ponassi, M., Biassoni, R., Conte, R., Spallarossa, A., Moretta, A., Moretta, L, Bolognesi, M. and Bordo D. (2002).
Crystallization and preliminary crystallographic characterization of the extracellular Ig-like domain of human Natural Killer cell activating receptor NKp44
Acta Crystallogr. D58, 1843 - 1845.

Bordo, D. and Bork, P. (2002).
Molecular and functional evolution of the rhodanese/Cdc25 phosphatase protein superfamily.
EMBO Reports, 3, 741 - 746.