YAC-1

Version 4.0.200811

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YAC-1 (mouse, A/Sn, lymphoma)

SPECIES: mouse, A/Sn
TUMOR: lymphoma

ECACC catalog code: 86022801
Morphology: Lymphoblast
TRANSFORMED BY: Moloney-MuLV
Description: Mouse lymphoma
Viruses: See Properties
Depositor: Prof H Harris/Dr C Madin, Sir William Dunn School of Pathology, Oxford, UK
No restrictions. Patent: None Specified By Depositor
Properties: Applications: NK assays

Available in the following LABORATORY:

Part of the Business Division of the Health Protection Agency (ECACC, Salisbury, Wiltshire)
RPMI 1640 + 2mM Glutamine + 10% Fetal Bovine Serum (FBS). Maintain cultures between 3-9x100,000 cells/ml; 5% CO2; 37C.
Induced by inoculation of Moloney leukaemia virus into a new-born A/Sn mouse. Sensitive to the cytotoxic activity of naturally occurring killer cells in mice (NK cells). Often used as target cells in NK assays.
Research council deposit: No; Price Code: B;
Validated by: isoenzymes (species confirmation)

Availability in cell line catalogues: ATCC: TIB 160, DSMZ: ACC 96

Bibliographic references:

Eur J Immunol 1975;5:112 - PMID: 1234049