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ECACC catalog code: 94102735
Description: Rat dorsal prostate adenocarcinoma
Viruses: See Properties
Depositor: Dr J Isaacs, Johns Hopkins Oncology Centre, Baltimore MD, USA (Originator)
No restrictions. Patent: None Specified By Depositor
Properties: Applications: Carcinogenesis studies, cytogenetic analysis
Available in the following LABORATORY:
Part of the Business Division of the Health Protection Agency (ECACC, Salisbury, Wiltshire)
RPMI 1640 + 2mM Glutamine + 250nM Dexamethasone (DXMT) + 10% Fetal Bovine Serum (FBS). Split confluent cultures 1:10 to 1:20 i.e. seeding at 2-4x1000 cells/cm2 using 0.25% trypsin/EDTA; 5% CO2; 37C.
Karyotype: Modal No. 85
MAT-Lu is one of a large series of cell lines of transplantable prostatic tumours originating from the spontaneous Dunning R-3327 rat prostatic cancer. The MAT-Lu cell line has been derived from a Metastatic-Anaplastic Tumour metastasising to the lungs (=MAT-Lu) and is androgen-independent.
Research council deposit: No;
Price Code: B;
Validated by: isoenzymes (species confirmation)
- Prostate 1988;13:165-188 - PMID: 3174494
For information, get in touch with:
Istituto Nazionale per la Ricerca sul Cancro,
c/o Centro Biotecnologie Avanzate, Torre B - Piano 2
Largo Rosanna Benzi, 10 - I-16132 Genova - Italy
Tel: +39-0105558-289, Fax: +39-0105558-293